Vol. 70 No. 3 (2024)

Original Research Articles

• Identification of small molecule inhibitors of penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus for the therapeutics of bacterial infection Inhibitors of PBP2a of methicillin-resistant S. aureus

  Razique Anwer

• Identification of DLEU2 as biomarker based on lncRNA-Mediated ceRNA network in rupture of intracranial aneurysm DLEU2: A lncRNA biomarker in intracranial aneurysm rupture

  Yanlei Gao, Tao Yu

• Identification of 10 differentially expressed and cuproptosis-related genes in immune infiltration and prognosis of thyroid Carcinoma The gene expression in TC

  Weixuan Yu, Haiping Liu, Yunda Zhang, Ming Liu, Weicong Li, Libin Wang, Dongwei Li

• Identification of important genes for human periodontal ligament cells in response to mechanical force based on WGCNA Important genes in HPDLC with mechanical force

  Xiaofeng Zhou

• In vivo determination of the anti-inflammatory and antioxidant effects of the aqueous extract of Syzygium aromaticum (clove) in an asthmatic rat model Antioxidant and anti-inflammatory effects of clove

  Lynda Sabrina Ounaceur, Nesrine Djaber, Anis Ounaceur, Abdelaziz Lankar, Mahfoud Messarah, Amel Boumendjel

• Identification of core genes of craniopharyngioma angiogenesis based on single-cell nuclear transcriptome sequencing Core genes in craniopharyngioma angiogenesis

  Jinshi Zhang, Lin Xu, Jiye Ye, Chunming Xu, Bowen Wu, Jie Wu, Tao Hong

• Importin 7 enhances protective autophagy induced by nuclear translocation of homeobox A10 in oral squamous cell carcinoma IPO7 enhances autophagy in OSCC

  Shanshan Chen, Jianbo Pan

• The relationship between preeclampsia risk and SENCR rs555172 gene polymorphism and expression SENCR expression and preeclampsia risk

  Mohsen Saravani, Mostafa Saeedinia, Majid Zaki-Dizaji, Marzieh Ghasemi, Sodabe Rezaei, Hamidreza Chegini, Roya Zanganeh, Sepehr Kahrizi, Hasan Dana, Elham Kazemi, Zohreh Heidary

• Small nucleolar RNA host gene 1 silence inhibits the lipopolysaccharide-induced microglial apoptosis and inflammation SNHG1 in SCI treatment

  Hongtao Shen, Jiaao Gu, Xing Liu, Mowei Song

• The tumor suppressor effect of miRNA 200-c-3p on A549 non-small cell lung cancer cell line is associated with down-regulation of programmed cell death ligand 1; an immune-check point mechanism MiRNA 200-c-3p in A 549 non-small cell lung cancer cell line

  Sara Ezzat, Magda I Mohamad, Manal Basyouni Ahmed, Sara Elsayed Abdelrahman, Nesma Hussein Abdel hay, Nashwa El-Khazragy, Maha Imam Ismail

• ATF3/EGR1 regulates myocardial ischemia/reperfusion injury induced autophagy and inflammation in cardiomyocytes ATF3/EGR1 control heart injury via autophagy & inflammation

  Li Li, Gang Fu, Caiyun Liu, Yanling Liu

• MiR-4454 in Combined Allergic Rhinitis and Asthma Syndrome (CARAS): Clinical significance and mechanistic insights into airway inflammation miR-4454 in CARAS

  Zhiguang Liu, Chuang Sun, Yujia Shi, Zhipeng Wang, Lianzheng Zhou, Qian Zhang, Zhengdao Mao

• Identification of hub genes and key pathways in spinal cord injury via bioinformatics analysis Bioinformatics analysis in SCI

  Hao Cheng, Yanben Wang, Jun Xuan

• The influence of genetic predisposition to oxidative stress on painful diabetic peripheral neuropathy: A mendelian randomization study Genetic oxidative stress impact on diabetic neuropathy pain

  Liyan Zou, Duosheng Zhu, Min Gong, Jiangyi Yu

• E-selectin is associated with stable angina and myocardial infarction in a sample of Kurdish population 7170G>C and stable angina and myocardial infarction

  Lajan Qasim Rahman, Ruqaya Muhammad Ghareeb

• Development of a novel six DNA damage response-related prognostic signature in osteosarcoma DNA damage in osteosarcoma

  Tianyang Li, Zhenzhou Tang, Sucheng Li, Minhua Lu

• Research of the unrecognised functions of mir-375 in prostate cancer cells Research on the effects of miR-375 in PCa

  Merve Goztepe, Onur Eroglu

• MicroRNA-503-5p protects streptozotocin-induced erectile dysfunction in diabetic rats by downregulating SYDE2 MicroRNA-503-5p protects ED by SYDE2

  Gangqin Li, Lin Jiang, Kuan Bai, Guangxing Tan

• "Simmer pus and grow flesh" method promotes chronic wound healing in rats via bFGF-Wnt β-catenin signaling pathway Enhancing wound healing via bFGF and Wnt pathways

  Zhenpeng Xu, Erwei Cai, Suyuan Shan, Cheng Zhao, Feng Lin, Yanyan Wu

• Ginsenoside Rc alleviates osteoporosis by the TGF-β/Smad signaling pathway Ginsenoside Rc alleviates osteoporosis

  Shanfu Wang, Bing Xu, Heng Yin, Zhen Hua, Yang Shao, Jianwei Wang

• DNMT1 methylation of LncRNA-ANRIL causes myocardial fibrosis pyroptosis by interfering with the NLRP3/Caspase-1 pathway DNMT1 methylation of ANRIL in myocardial fibrosis

  Zuntao Liu, Lei Gao, Chenjing Kan, Xin Chen, Kaihu Shi, Wei Wang

• Clinical value of KiSS-1 and MMP-2 expression levels in breast cancer tissue in evaluating prognosis of elderly breast cancer patients after modified radical mastectomy KiSS-1 and MMP-2 expression in breast cancer

  Jiyang Lv, Junya Zhang, Fangfang Wu

• Knockdown of lncRNA AU020206 could inhibit microglia apoptosis in ischemic stroke Inhibiting AU020206 aids ischemic stroke microglia survival

  Zhihua Chen, Wei Hu, Jiahong Wang, Donggen Rao, Jianming Zhu

• MiR-34a ameliorates arterial blood flow in rats with lower limb arteriosclerosis obliterans via Sirt1 signaling pathway MiR-34a in rats with lower limb arteriosclerosis obliterans

  Tuo Xu, Changwei Zheng, Yongkang Wu, Zhengde Chen, Huilai Miao

• Identification of osteogenic differentiation-related miRNA-mRNA regulatory network of human periodontal ligament stem cells Osteogenic differentiation-related miRNA-mRNA regulatory network

  Zhenrong Chen, Lulu Long, Mianjia Wan, Min Huang, Haijuan Wu, Qun Huang

• Diagnostic value of high-frequency ultrasound combined with fine needle aspiration cytology and BRAF gene for papillary thyroid microcarcinoma BRAF diagnostic in PTMC

  Chuang Li, Xiaojuan Zhao, Jingge Zhao, Jing Zhao, Lemei An, Gang Wu

• Effect of NAMPT on the proliferation and apoptosis in odontoblast-like MDPC-23 cell Effect of NAMPT on MDPC-23 cell survival

  Kyeong-Rok Kang, Jae-Sung Kim, Jeong-Yeon Seo, HyangI Lim, Hong Sung Chun, Sun-Kyoung Yu, Heung-Joong , Joo-Cheol Park, Do Kyung Kim

• Lactoferrin mediates epithelial-mesenchymal transformation by regulating the PI3K/AKT/mTOR pathway to inhibit nasopharyngeal carcinoma metastasis Lactoferrin inhibits NPC metastasis via PI3K/AKT/mTOR pathway

  Min Xu, Ye Fan, Guoying Zou, Qi Yang, Fei Xu

• The therapeutic effects of ADSCs on photoaging of skin induced by UVB irradiation ADSCs' impact on UVB-induced Skin photoaging

  Jing Wang, Xiaochen Zhou, Di Cao, Ying Meng, Yingchun Wang, Debin Yang

• Antibacterial effect and biocompatibility of silver nanoparticle-coated bone allograft substitutes Antibacterial AgNPs for bone allograft infection

  Sanna Hadi, Othman Omar

• Chelerythrine induces apoptosis and ferroptosis through Nrf2 in ovarian cancer cells Chelerythrine triggers cell death via Nrf2 in ovarian cancer

  Jia Zhou, Zhidong Qiu, Fang Zhou, Guo Xin, Ning Kong, Guangfu Lv, He Lin, Zhe Lin, Yangxin Fu, Yuchen Wang, Xiaowei Huang

• Association of IL-1β 542 T>A gene polymorphism with Recurrent Aphthous Stomatitis in Erbil City population Association of IL-1β 542 T>A gene polymorphism with RAS

  Asma Qasim Rahman, Reiadh Kamal Al-Kamali

• Comprehensive bioinformatics analysis of KIF20A as a prognosis biomarker for clear cell renal cell carcinoma KIF20A prognosis biomarker in clear cell RCC

  Cankun Xie, Wingkeung Yiu, Yijiang Mo

• Molecular mechanism of high glucose-induced mitochondrial DNA damage in retinal ganglion cells High glucose-induces mitochondrial DNA damage in retinal cells

  Jinzi Zhou, Fenghua Chen, Aimin Yan, Xiaobo Xia

• MiR-4319 targets tuftelin 1 to reduce malignancy of cervical cancer cells MiR-4319 tuftelin 1 in CC

  Lijun Zheng, Qiongzhen Ren, Weipei Zhu, Xiaomin Tao, Liangsheng Guo

• Knockdown of growth differentiation factor-15 restrains prostate cancer through regulating MAPK/ERK signaling pathway GDF15 affects prostate cancer via MAPK/ERK

  Minggen Yang, Miaolin Guo, Chenqiang Su, Weiping Hao, Zhenqiang Xu

• TNFRSF6 induces mitochondrial dysfunction and microglia activation in the in vivo and in vitro models of sepsis-associated encephalopathy TNFRSF6 promotes sepsis-associated encephalopathy

  Danfeng Yu, Yanmei Ji, Jing Zhang, Xiaochuan Huang

• circ_JMJD1C expedites breast cancer progression by regulating miR-182-5p/JMJD1C/SOX4 axis The roles of circ_JMJD1C in breast cancer

  Renyuan Xu, Haomiao Lan, Li Zhang, Sisi Yang, Yu Mao, Hongying Che